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What we learnt from the COVID-19 pandemic

In early 2020, the health sector in India was about to shift gears from the policy formulation stage to the implementation stage. It is at this point that the pandemic happened. The importance of having a robust public health system has never been felt more acutely. We have learnt a few things in these nine months into the pandemic, excerpted from Till We Win: India’s Fight against the COVID-19 Pandemic by Dr Chandrakant Lahariya, Dr Gagandeep Kang and Dr Randeep Guleria.

Well-functioning primary healthcare services as well as stronger public health services are essential to keep the society healthy: A majority of COVID-19 patients, nearly 80 per cent, needed only an initial interaction with health systems and no medical intervention during the entire period of recovery. They were either kept at CCCs, mainly to isolate them from healthy individuals, or were allowed home isolation. Such an approach reduced the risk of these patients transmitting the virus to others while visiting large facilities to seek care. Most of the interventions, be it contact tracing, testing, isolation or advising people on COVID-19-appropriate behaviour, were being delivered by primary care and public health staff. It is for this reason that countries with a stronger primary healthcare system (such as Thailand and Vietnam) fared much better than countries with a hospital-centric health system. Taiwan largely controlled the pandemic through effective testing and contact-tracing approaches, delivered through the primary healthcare and public health teams.

Neighbourhood clinics play a bigger role in ensuring good health than large hospitals: The pandemic has shown us the utility of smaller facilities over mega hospitals. In the early period of the outbreak, big hospitals became overburdened as all suspected and sick people thronged them. Panic led even patients with mild illness to rush to these hospitals. This drove home the point that a good referral system helps in balancing out the load of patient care and ultimately leads to better patient care. During the period of the pandemic, a majority of COVID-19 and non-COVID-19 services were provided by the PHCs and neighbourhood clinics.

front cover till we win
Till We Win||Dr Randeep Guleria, Dr Gagandeep Kang, Dr Chandrakant Lahariya

Health is about a broad range of services and providers:

To stay healthy, we all need much more than hospitals and doctors. Health services are a combination of public health (preventive, promotive services) as well as medical care (clinical/curative services), among others. If it were not for preventive and promotive health services, which help in reducing disease, hospital services would never be enough to treat all the people who get sick. Also, health needs multi-sectoral inputs, and the importance of sanitation and infection-control measures have now become more evident. Focusing on only one type of service will not suffice.

Non-pharmacological interventions are equally important and effective: The war against COVID-19 has largely been fought by people adopting and adhering to the non- pharmacological interventions or ‘the social vaccines’ of wearing a face mask, handwashing, and physical distancing. Till (and even after) effective therapies or a few vaccines become available, these interventions will continue to play a key role in decreasing the disease burden. Other than for COVID-19, there are many non-pharmacological interventions that are proven against diseases such as diabetes and hypertension: healthy diet, regular physical activity, no smoking and moderate or no use of alcohol. It is time that the approach of encouraging people to adopt a healthy behaviour becomes mainstream for other health conditions as well.

Laboratory testing and diagnostic services are an important part of overall health service delivery: Testing can help in early identification of infection, prevent the spread of disease, and guide early interventions. This is also applicable for health services in non-emergency times. Testing forms the basis for other strategies which are planned at local and national levels and must be pursued aggressively.

Better functioning government-funded health systems are more effective in an early response to epidemics and pandemics: Pandemics are unprecedented challenges and no health system is fully prepared to respond to these without additional efforts. However, stronger health systems funded by governments mount a more effective response, which also allows for surge capacity.

Health services entail teamwork between health and non- health contributors: Keeping people safe and healthy requires interventions across a broad range of services, including testing for identification of those with infection, tracing the healthy who have been exposed and are at risk of falling sick, isolating those who are sick and can transmit infection, treatment for those who need medical care, and so on. For all of these, we need not only doctors and nurses, but also pharmacists, laboratory technicians and frontline workers. We also need coordination and collaboration with sanitation workers and community members. The pandemic has taught us that to tackle health issues comprehensively we need to move out of silos. Multi-sectoral collaboration is essential for comprehensive preventive and curative health.

Frontline workers are at the heart of health services: When the history of the fight against COVID-19 is documented, the efforts of frontline workers from the ASHAs, AWWs to ANMs will find a special mention. They are the ones who have guided the health system from the field and tracked the infection in the community. They perform yeomen services even during non-pandemic periods.

The health sector faces a paucity of essential supplies needed for delivering services: The shortage of PPE in the initial stage of the outbreak and, subsequently, a shortage of medical oxygen can be taken as indicative of supply issues in the health sector in India. Although the shortage was eventually addressed, this needs to be monitored on a regular basis. These shortages are indicative of an overall shortage of various types of supplies, such as medicines, diagnostic kits and other consumables.

Other things we learnt, specified in more detail in the book are:

  • The private sector has a role to play in health services which can be harnessed with effective regulation.
  • Health sector laws and regulations should be better implemented.
  • Health and economy are interlinked.
  • There is a huge role of epidemiological, operational and scientific research in advancing health.
  • Health outcomes are dependent on collaboration and community participation.

 

Offering insights on how India continues to fight the pandemic, Till We Win is a must-read for everyone. It is a book for the people, for political leaders, policymakers and physicians, with the promise and potential to transform public health in India.

 

 

 

India and the COVID-19 vaccine

The COVID-19 vaccine: a favourite topic in the present day. When will it arrive? Why are they taking so long? And most importantly, do we really need them, or is herd immunity enough in a country like ours?

In this article we try and answer these questions, from Dr Chandrakant Lahariya, Dr Gagandeep Kang and Dr Randeep Guleria.

India is the largest producer (by volume or number of doses) of vaccines in the world, and provides vaccines to UNICEF which then distributes them in Africa, South America and Asia. For UNICEF to buy the vaccines, the vaccines have to be pre-qualified or approved for purchase by the WHO. The WHO’s approval process relies on the fact that the country which makes the vaccines has a national regulatory authority that meets the standards laid down by the WHO. India’s CDSCO has met these criteria and ensures that the vaccines made in India are of high quality and safe. Indian vaccine manufacturers, which have grown in number and capacity since they were established decades ago, have good and long experience with manufacturing in high volumes. However, they have only recently begun modest investments in research towards new vaccines. With a population of 138 crore, India needs local and indigenous production of the COVID-19 vaccine to ensure widespread availability.

front cover till we win
Till We Win||Dr Randeep Guleria, Dr Gagandeep Kang, Dr Chandrakant Lahariya

The development and availability of the vaccine in India has been part of some of the early discussions on the country’s response to the COVID-19 pandemic. A national task force for vaccine research and development was set up in April 2020. The progress on the vaccines, both globally and in India, has been reviewed by high-level committees, and planning for delivery of the vaccines is ongoing. In early October 2020, the health minister announced a proposal to vaccinate 20 to 25 crore Indians by July 2021. In parallel with many such efforts around the world, discussions are on about the prioritization of target populations for initial vaccination.

 

When can we expect the first vaccine against COVID-19?

Till October 2020, six vaccines had been given limited licence in China and Russia. While a definite timeline is difficult to predict, there is a possibility that some vaccines may be available by early 2021. However, vaccination will be an ongoing process and it will be two to three years before sufficient vaccines are available to vaccinate all those in need.

 

There are a number of vaccines in the last stage of clinical trials, why is it taking so much time?

It is true that there are COVID-19 vaccines in phase III of clinical trials across the world, with trials starting in India. However, there are no guaranteed successes, and we need to wait for the results to know what works and what does not. If successful, the data need to be submitted to the regulatory authorities for approval. This is followed by production by one or more vaccine companies and then supply, resulting finally in availability. All these steps are expected to take some time.

 

What is herd immunity? Do we really need COVID-19 vaccines or is herd immunity enough?

Herd immunity is also called herd effect, community immunity, population immunity or social immunity. It is a form of indirect protection from infectious disease which happens when a defined proportion of the population has been infected and has become immune to an infection. As an increasing number of people are infected or vaccinated, the number of people who can be infected (‘susceptibles’) decreases and transmission or spread also decreases. When herd immunity is reached, it is important to note that this is a feature that works at the population level—a decrease in spread within a defined group; it is not perfect protection of all uninfected people. At the individual level, the status of immunity depends on that person’s exposure or vaccination status. This means that if a susceptible individual is no longer within the ‘herd’, then they are likely to be infected on exposure, and are not ‘immune’.

When the level of infection or vaccination that is required is calculated, then the basic reproductive rate of the virus has to be known. The higher the reproductive rate, the greater the proportion of the herd that needs to be infected or vaccinated to prevent the spread. For measles, which is very infectious, we would like to reach 95 per cent vaccination to prevent outbreaks. At this time, data from sero-surveys in India shows 7 per cent seropositivity in a national survey at the end of August but pockets of high positivity in urban areas (56 per cent in some localities in Mumbai and 51 per cent in areas of Pune and 29 per cent in Delhi). This indicates that herd immunity is still far for most of the country, and we should be looking to a vaccine for more predictable development of immunity.

Offering insights on how India continues to fight the pandemic, their book Till We Win is a must-read for everyone. It is a book for the people, for political leaders, policymakers and physicians, with the promise and potential to transform public health in India.

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